Method for lyophilizing an active agent

Details Method for lyophilizing an active agent Method for lyophilizing an active agent

F - Mech Eng,Light,Heat,Weapons

26

B

F26B 5/06 (2006.01) A61M 5/178 (2006.01)

Patent

CA 2519367

A process for lyophilizing a solution (50) of an active agent in a container (19) is provided. Solution of active agent is deposited into a container, the container is covered with a covering plate (60) and placed inside a lyophilizing apparatus. Lyophilization can be conducted to dryness by radiation, convection or both. Also provided is a device made by this process, an active agent-plastic administration device (e.g., a syringe (20)), containing an active agent in the form of lyophilized cake, and an array of such administration devices.

L'invention concerne un procédé de lyophilisation d'une solution (50) d'un principe actif dans un récipient (19). La solution du principe actif est déposée dans un récipient qui est recouvert d'une plaque couvercle (60) et placé dans un appareil de lyophilisation. Le processus de lyophilisation peut être mené jusqu'à sécheresse par rayonnement, convection ou par les deux. L'invention concerne également un dispositif réalisé par ce procédé, soit un dispositif en plastique destiné à administrer le principe actif (par exemple une seringue (20)), contenant un principe actif sous la forme d'un gâteau lyophilisé, et une grille de tels dispositifs d'administration.

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