Method for making a preconjugate

Details Method for making a preconjugate Method for making a preconjugate

C - Chemistry, Metallurgy

07

H

C07H 15/22 (2006.01) C07H 15/234 (2006.01) C07H 17/08 (2006.01) C07H 23/00 (2006.01) G01N 33/531 (2006.01) G01N 33/539 (2006.01)

Patent

CA 2130170

2130170 9416330 PCTABS00033 A method for making a preconjugate comprising an immunogenic species of a polymorphic analyte is disclosed. The method is carried out by reacting an activated binding moiety, and a polymorphic analyte at room temperature for between about 10 hours and about 60 hours. The attaching reaction results in an excess of the preconjugate comprising the immunogenic species of the polymorphic analyte. The preconjugate can be used to make an immunoreactive conjugate useful as a developer antigen in a competitive inhibition immunoassay for the polymorphic analyte.

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