Method for making a self-assembling monolayer and composition

Details Method for making a self-assembling monolayer and composition Method for making a self-assembling monolayer and composition

C - Chemistry, Metallurgy

09

D

C09D 201/02 (2006.01) B05D 1/18 (2006.01) B05D 3/06 (2006.01) C09D 125/06 (2006.01) C09D 127/06 (2006.01) C09D 175/04 (2006.01) C09D 183/04 (2006.01) C09D 201/00 (2006.01)

Patent

CA 2453573

A surface coating composition for providing a self-assembling monolayer, in stable form, on a material surface or at a suitable interface, as well as a method of preparing such a composition and a method of using such a composition to coat a surface, such as the surface of an implantable medical device, in order to provide the surface with desirable properties. The method provides the covalent attachment of a SAM to a surface in a manner that substantially retains or improves the characteristics and/or performance of both the SAM and the surface itself. Covalent attachment is accomplished by the use of one or more latent reactive groups, e.g., provided by either the surface and/or by the SAM-forming molecules themselves.

Cette invention concerne une composition de revêtement de surface permettant d'obtenir une monocouche auto-assemblée, dans une forme stable, sur une surface de matière ou sur une interface appropriée, ainsi qu'un procédé de préparation de cette composition et un procédé d'utilisation de cette composition pour enduire une surface, telle que la surface d'un dispositif médical implantable, afin de conférer à cette surface les propriétés souhaitées. Ce procédé permet d'obtenir la fixation covalente d'une monocouche auto-assemblée sur une surface de manière que les caractéristiques et/ou les performances à la fois de la monocouche auto-assemblée et de la surface soient sensiblement conservées ou améliorées. La fixation covalente est effectuée par l'utilisation d'un ou plusieurs groupes réactifs latents obtenus à partir de la surface et/ou des molécules de formation de monocouche auto-assemblée.

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