Method for making an amine and an alkyl ester

Details Method for making an amine and an alkyl ester Method for making an amine and an alkyl ester

C - Chemistry, Metallurgy

07

C

C07C 69/06 (2006.01) C07C 67/22 (2006.01) C07C 209/60 (2006.01) C07C 209/62 (2006.01) C07C 211/03 (2006.01)

Patent

CA 2156698

A method for making an amine includes the steps of heating a reaction mixture including a nitrile, an acid, water and a substrate compound capable of generating a carbonium ion by reaction with the acid to generate a first reaction intermediate; treating the first reaction intermediate with an acid in the presence of a primary alkanol to form a second reaction intermediate and an alkyl ester; separating the alkyl ester from the second reaction intermediate; and treating the second reaction intermediate with a base to form the amine.

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