Method for making an implantable biocompatible material with...

A - Human Necessities – 61 – L

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A61L 27/02 (2006.01) A61F 2/02 (2006.01) A61F 2/28 (2006.01) A61K 6/00 (2006.01) A61L 27/06 (2006.01) A61L 27/58 (2006.01) A61L 31/02 (2006.01)

Patent

CA 2655184

The invention concerns a method for making a biocompatible material implantable in a human or animal body including: a step (a) of dispersing at least one biocompatible substance in a solvent, to obtain an intermediate solution; a step (b) of condensation of said intermediate solution to obtain an amorphous condensate of said biocompatible substance; a step (c) of mixing the biocompatible substance with at least one agent for nucleating said biocompatible substance; a step (d) of activating the nucleating agent to generate the development, within said amorphous condensate, a mixed pseudo-crystalline lattice consisting of both the biocompatible substance and the nucleating agent, so as to obtain a biocompatible material at least partly crystallized. The invention also concerns biocompatible materials implantable in a human or animal body.

L'invention concerne un procédé de fabrication d'un matériau biocompatible implantable dans un corps humain ou animal comprenant : - une étape (a) de dispersion d'au moins une substance biocompatible dans un solvant, conduisant à l'obtention d'une solution intermédiaire, - une étape (b) de condensation de ladite solution intermédiaire, conduisant à l'obtention d'un condensat amorphe de ladite substance biocompatible, - une étape (c) de mélange de la substance biocompatible avec au moins un agent nucléant de cette substance biocompatible, - une étape (d) d'activation de l'agent nucléant pour générer le développement, au sein dudit condensât amorphe, d'un réseau pseudo-cristallin mixte formé à la fois par la substance biocompatible et l'agent nucléant, de façon à obtenir ainsi un matériau biocompatible au moins partiellement cristallisé. Matériaux biocompatibles implantables dans un corps humain ou animal.

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