Method for making antibody fc-heterodimeric molecules using...

Details Method for making antibody fc-heterodimeric molecules using... Method for making antibody fc-heterodimeric molecules using...

C - Chemistry, Metallurgy

07

K

C07K 16/46 (2006.01)

Patent

CA 2709847

The invention relates to methods of making Fc-heterodimeric proteins or polypeptides. The invention also relates to the Fc-heterodimeric proteins or polypeptides themselves, including the individual polypeptide components that comprise the heterodimer. Nucleic acids encoding such polypeptides, expression vectors, and host cells. Moreover, the invention relates to phar-maceutical compositions comprising one of more Fc-heterodimeric proteins or polypeptides.

Cette invention concerne des méthodes de fabrication de polypeptides ou de protéines hétérodimères Fc. L'invention concerne également ces mêmes polypeptides/protéines hétérodimères Fc, y compris chacun des composants polypeptidiques qui constituent l'hétérodimère. L'invention concerne par ailleurs des acides nucléiques codant ces polypeptides, des vecteurs d'expression et des cellules hôtes. Par ailleurs, l'invention concerne des compositions pharmaceutiques comprenant l'un(e) des polypeptides ou des protéines hétérodimères Fc.

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