A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 31/495 (2006.01) A61K 31/496 (2006.01) A61K 47/48 (2006.01)
Patent
CA 2734691
In one aspect, the present invention features a method of producing a tablet including cetirizine including the steps of: (i) mixing cetirizine, a polyol, and a solvent for the cetirizine to form a cetirizine:polyol complex, wherein the solvent comprises water and an alkalizing agent and has a pH from about 2 to about 7; (ii) isolating particles of the cetirizine:polyol complex from the mixture; and (iii) forming the particles into a tablet.
Sous un aspect, la présente invention porte sur un procédé de production d'un comprimé comprenant de la cétirizine. Le procédé comprend les étapes consistant à : (i) mélanger de la cétirizine, un polyol et un solvant pour que la cétirizine forme un complexe cétirizine:polyol, le solvant comprenant de l'eau et un agent alcalisant et ayant un pH d'environ 2 à environ 7 ; (ii) isoler les particules du complexe cétirizine:polyol du mélange ; et (iii) mettre les particules sous forme de comprimé.
Day Kenneth
Kamath Satish
Shah Indu
Xiao Kangping
Mcneil-Ppc Inc.
Smart & Biggar
LandOfFree
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