Method for making coated gabapentine or pregabaline particles

A - Human Necessities – 61 – K

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A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 9/50 (2006.01) A61K 31/195 (2006.01)

Patent

CA 2338173

The invention concerns a method for making coated particles of .gamma.-aminobutyric acid analogue whereof the lactam content by weight relative to the weight of .gamma.-aminobutyric acid analogue is less than 0.5 %. The invention is characterised in that it consists in spraying a coating solution comprising at least a polymer in an organic solvent on said .gamma.-aminobutyric acid analogue particles.

Procédé pour la fabrication de particules d'analogue d'acide .gamma.- aminobutyrique enrobées dont la teneur en lactame en poids par rapport au poids d'analogue d'acide .gamma.-aminobutyrique est inférieure à 0,5 %, caractérisé en ce que l'on pulvérise une solution d'enrobage comprenant au moins un polymère dans un solvant organique sur lesdites particules d'analogue d'acide .gamma.-aminobutyrique.

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