Method for making homogeneous spray-dried solid amorphous...

Details Method for making homogeneous spray-dried solid amorphous... Method for making homogeneous spray-dried solid amorphous...

A - Human Necessities

61

K

A61K 9/16 (2006.01) A61K 9/14 (2006.01)

Patent

CA 2472028

Conventional spray-drying methods are improved by incorporation of a pressure nozzle and a diffuser plate to improve the flow of drying gas and a drying chamber extention to increase drying time, such improvements leading to the formation of homogeneous solid dispertions of drugs in concentration-enhancing polymers.

Selon l'invention, pour améliorer les procédés classiques de séchage par pulvérisation, on incorpore une buse de projection et une plaque diffuseuse afin d'améliorer l'écoulement du gaz de séchage et un prolongement de la chambre de séchage afin d'augmenter le temps de séchage, ces améliorations entraînant la formation de dispersions solides homogènes de médicaments dans des polymères renforçant la concentration.

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