Method for making medical devices having antimicrobial...

A - Human Necessities – 61 – L

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A61L 27/34 (2006.01) A61L 27/54 (2006.01) A61L 29/10 (2006.01) A61L 29/16 (2006.01) A61L 31/08 (2006.01) A61L 31/10 (2006.01) G02B 1/04 (2006.01)

Patent

CA 2508263

The present invention provides a method for preparing a medical device, preferably a contact lens, having an antimicrobial metal-containing LbL coating on a medical device, wherein the antimicrobial metal-containing LbL coating comprises at least one layer of a negatively charged polyionic material having -COOAg groups and/or silver nanoparticles formed by reducing Ag+ ions associated with the -COO- groups of the negatively charged polyionic material. In addition, the present invention provides a medical device prepared according to a method of the invention.

L'invention concerne un procédé de préparation d'un dispositif médical, de préférence une lentille de contact, présentant un revêtement LbL antimicrobien contenant du métal sur la surface de ce dispositif médical. Le revêtement LbL antimicrobien contenant du métal comprend au moins une couche de matière polyionique chargée négativement, présentant des groupes - COOAg et/ou des nanoparticules d'argent formées par la réduction d'ions Ag?+¿ associés aux groupes -COO?-¿ de la matière polyionique chargée négativement. En outre, l'invention concerne un dispositif médical préparé selon le procédé de l'invention.

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