Method for making pharmaceutical multiparticulates

Details Method for making pharmaceutical multiparticulates Method for making pharmaceutical multiparticulates

A - Human Necessities

61

K

A61K 9/16 (2006.01) A61K 31/7052 (2006.01)

Patent

CA 2547774

A process for forming drug multiparticulates having improved drug crystallinity is disclosed, comprising modifying a conventional melt-congeal process by adding a volatile cospecies either to the molten mixture or to the process atmosphere, or to both.

Procédé de fabrication de formes multiparticulaires d'un médicament présentant un cristallinité médicamenteuse améliorée, consistant à modifier un procédé de congélation/fusion classique par addition d'une co-espèce volatile, soit au mélange fondu soit à l'atmosphère dans laquelle se déroule le procédé, ou encore aux deux.

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