Method for making uniformly-sized particles from insoluble...

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B01J 13/00 (2006.01) A61J 3/02 (2006.01) A61K 9/14 (2006.01) A61K 9/16 (2006.01) A61K 49/04 (2006.01) B01D 21/26 (2006.01)

Patent

CA 2089075

2089075 9203380 PCTABS00010 The invention involves a method for making uniformly sized particles from solid compounds. First, a suitable solid compound is dissolved in a suitable solvent. Then, a precipitating liquid is infused, precipitating non-aggregated particles with substantially uniform mean diameter. The particles are then separated from the solvent. Depending on the solid compound and the desired particle size, the parameters of temperature, ratio of non-solvent to solvent, infusion rate, stir rate, and volume can be varied according to the invention. The precipitating liquid may be aqueous or non-aqueous, depending upon the relative solubility of the compound and the desired suspending vehicle.

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