Method for manufacturing neuraminic acid derivatives

Details Method for manufacturing neuraminic acid derivatives Method for manufacturing neuraminic acid derivatives

C - Chemistry, Metallurgy

07

D

C07D 309/28 (2006.01) A61K 31/351 (2006.01) C07C 41/00 (2006.01) C07C 41/60 (2006.01) C07D 407/06 (2006.01) C07D 498/04 (2006.01)

Patent

CA 2683065

A method for manufacturing neuraminic acid derivatives is provided, also synthetic intermediates of the neuraminic acid derivatives and methods for their manufacture, and neuraminic acid derivatives having high purity. [Means for solution] A synthetic intermediate compound represented by the formula (7) is provided: [wherein R3 represents alkyl; R4 and R5 each represents H, alkyl, phenyl, or together represent tetramethylene, pentamethylene, oxo].

L'invention se rapporte à un procédé de fabrication de dérivés de l'acide neuraminique, à des intermédiaires synthétiques de l'acide neuraminique et à des procédés de fabrication de ces derniers, et à des dérivés de l'acide neuraminique de grande pureté. L'invention concerne un composé d'intermédiaire synthétique représenté par la formule (7) : [dans laquelle R3 représente alkyle; R4 et R5 représentent chacun H, alkyle, phényle, ou représentent ensemble tétraméthylène, pentaméthylène, oxo].

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