C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01)
Patent
CA 2710807
The present invention relates to a method for measuring the copy number of a chromosome, gene or specific nucleotide sequence, comprising the steps of: (a) mixing a homozygous DNA with a test sample DNA; (b) analyzing the DNA mixture by means of SNP array; and (c) determining the copy number of a chromosome, gene, or specific nucleotide sequence by measuring the difference in signal output from the homozygous DNA and the test sample DNA.
L'invention concerne un procédé d'évaluation de nombre de copies de chromosome, gène ou séquence nucléotidique spécifique, comme suit: (a) mélange d'ADN homozygote et d'ADN de spécimen d'essai, (b) analyse du mélange d'ADN reposant sur l'utilisation d'un jeu SNP, et (c) détermination du nombre de copies de chromosome, gène ou séquence nucléotidique spécifique par évaluation de la différence de sortie des signaux depuis l'ADN homozygote et l'ADN de spécimen d'essai.
National Cancer Center
Ridout & Maybee Llp
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