Method for measuring resistance or sensitivity to docetaxel

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01)

Patent

CA 2589918

The present invention relates to novel and useful methods that predict or monitor a patient~s reponse to a molecule of the taxoid family by measuring the increase or decrease of specific genetic markers as compared to controls. The present invention also provides kits that predict of monitor patient~s response to a molecule of the taxoid family by measuring nucleid acid or protein levels of particular genetic markers and comparing their levels to controls or reference markers.

La présente invention concerne de nouvelles méthodes utilisées dans la prévision ou la surveillance de la réponse d'un patient à une molécule de la famille des taxoïdes, par mesure de l'augmentation ou de la réduction de marqueurs génétiques spécifiques par rapport aux témoins. La présente invention concerne également des kits de prévision ou de surveillance de la réponse des patients à une molécule de la famille des taxoïdes, par mesure des niveaux d'acides nucléiques ou de protéines de marqueurs génétiques particuliers, et par comparaison de ces niveaux aux témoins ou marqueurs de référence.

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