Method for measuring the free fraction of ligands in...

G - Physics – 01 – N

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

167/41

G01N 33/53 (2006.01) G01N 33/543 (2006.01) G01N 33/544 (2006.01) G01N 33/577 (2006.01) G01N 33/74 (2006.01) G01N 33/78 (2006.01)

Patent

CA 1340536

A one-step assay for the free portion of a ligand in a biological sample involves incubating a mixture of the sample with a labelled antibody for the ligand and a ligand analogue which competes with the ligand for binding to the antibody. The assay is characterized by using a monoclonal antibody and by choosing a ligand analogue which has a lower affinity for the antibody than does the ligand. An insolubilised ligand analogue preferably has a binding affinity for the antibody from 0.01% to 10% of that of the ligand. Ligand/ligand analogue pairs exemplified are T4/T3 (Thyroxine/Tri- iodothyronine); Testosterone/etiocholanol; and T3/T2.

587598

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Method for measuring the free fraction of ligands in... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for measuring the free fraction of ligands in..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for measuring the free fraction of ligands in... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1319370

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.