Method for modeling signal transduction in cells

Details Method for modeling signal transduction in cells Method for modeling signal transduction in cells

G - Physics

06

G

G06G 7/48 (2006.01)

Patent

CA 2466112

The present invention provides a model that can be use to describe biological processes having a complex spatial geometry, for example, cell signaling processes. The models can also be used to model the pathology underlying diseases characterized by disrupted signaling pathways, and to identify target proteins at an appropriate site in a signal transduction network such that modulation of the target proteins elicits therapeutic effects. Methods of modeling diffusion processes, as well as machine-readable products embodying the methods are also disclosed.

La présente invention concerne un modèle qui peut s'utiliser pour décrire des processus biologiques possédant une géométrie spatiale complexe, par exemple, des processus de signalisation dans les cellules. Les modèles peuvent aussi s'utiliser pour modéliser la pathologie accompagnant des maladies caractérisées par la perturbation des voies de signalisation et pour identifier les protéines cibles sur un site approprié dans un réseau de transduction de signaux, de manière à ce que la modulation des protéines cibles élicite les effets thérapeutiques. L'invention concerne également les procédés de modélisation des processus de diffusion ainsi que des produits lisibles par machine fondés sur ces procédés.

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