Method for modifying, diagnosing, and screening for igf-i...

A - Human Necessities – 61 – K

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A61K 38/30 (2006.01) C07K 14/65 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2132871

2132871 9416722 PCTABS00033 A method of chronic modification of cell barrier properties by exposing a cell to a modification-effective amount of IGF-I for at least about 7 days wherein the modification effective amount is between about 50 µg/kg and less than about 500 µg/kg is disclosed. Further disclosed is a method of chronic amelioration or reversal of insulin resistance as well as a method of diagnosing and screening for rhIGF-I sensitive cell barrier properties.

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