Method for modifying the cell tissue or host tropism of a...

Details Method for modifying the cell tissue or host tropism of a... Method for modifying the cell tissue or host tropism of a...

C - Chemistry, Metallurgy

12

N

C12N 15/86 (2006.01) A61K 39/245 (2006.01) C07K 14/03 (2006.01) C12N 7/01 (2006.01) C12N 15/85 (2006.01) C12N 15/869 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2089484

2089484 9203563 PCTABS00011 The invention relates to a microorganism having a modified cell, tissue or host tropism whereby at least one gene of the microorganism, preferably an essential gene, is brought under the control of a nucleotide sequence specific for the cell, the tissue or the host. The specific nucleotide sequence can be a promoter sequence and/or enhancer sequence, which can be inducible. The invention is also directed at the use of such a recombinant microorganism for the provision of protection against the corresponding natural microorganism.

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