Method for modulating calcium ion-release-activated calcium...

A - Human Necessities – 61 – K

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Details

A61K 31/535 (2006.01) A61K 31/40 (2006.01) A61K 31/41 (2006.01) A61K 31/415 (2006.01) A61K 31/42 (2006.01)

Patent

CA 2533598

The invention relates to a method for modulating Ca 2'-release-activated Ca 2+ channels (CRAG) in a cell by administering to the cell a compound of formula (I): or a pharmaceutically acceptable salt, solvate, clathrate, or prodrug thereof wherein X, Y, A, Z, L and n are defined herein.

La présente invention a trait à un procédé de modulation de procédé de canaux d'ions calcium activés par la libération d'ions calcium dans une cellule par l'administration à la cellule d'un composé de formule (I) dans laquelle X, Y, A, Z, L et n sont tels que définis dans la description ; ou un sel, solvate, clathrate, ou prodrogue de celui-ci.

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