Method for modulating gene expression by altering the cpg...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/63 (2006.01)

Patent

CA 2575490

The invention relates to nucleic acid modifications for a directed expression modulation by the targeted insertion or removal of CpG dinucleotides. The invention also relates to modified nucleic acids and expression vectors.

L'invention concerne des modifications d'acide nucléique pour une modulation orientée de l'expression par insertion ciblée ou extraction ciblée de dinucléotides CpG. La présente invention porte également sur des acides nucléiques modifiés et sur des vecteurs d'expression.

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