Method for modulating macrophage activation

A - Human Necessities – 61 – K

Patent

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A61K 31/185 (2006.01) A61P 25/28 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01)

Patent

CA 2632106

Anionic compounds, including sulfonates, are capable of blocking A.beta.- induced macrophage activation (or macrophage activation induced by other amyloidogenic proteins or peptides). Such compounds can inhibit the inflammatory process, e.g., in the brain of a subject suffering from a disease characterized by A8 deposition, such as Alzheimer's disease.

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