C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/10 (2006.01) A01K 67/027 (2006.01) C12Q 1/02 (2006.01)
Patent
CA 2385187
The invention relates to cells, to an animal model and to methods for observing human endometrial cells in a living animal and more particularly for visualizing human endometriotic lesion implantation, progression and regression in live intact animals through whole body imaging. The invention is based on the non-invasive detection of fluorescent endometrial cells and tissue in dynamic and real-time settings. Animals containing fluorescent endometriotic lesions represent a useful model for studying the mechanisms of the disease, as well as potent tools for pre- clinical in vivo testing of pharmaceutical agents or gene products targeting endometriosis.
Hugo Patrice
Steff Ann-Muriel
Metriogene Biosciences Inc.
Procrea Biosciences Inc.
Robic
LandOfFree
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