Method for obtaining a natural mixture of conjugated equine...

C - Chemistry – Metallurgy – 07 – J

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C07J 75/00 (2006.01)

Patent

CA 2529009

A method for obtaining an extract containing the natural mixture of conjugated equine oestrogens is described, wherein the mixture of conjugated oestrogens obtained by solid- phase extraction from pregnant mares' urine is depleted in phenolic urine contents and in non-conjugated lipophilic compounds from the group comprising non-conjugated flavonoids, non-conjugated isoflavonoids, non-conjugated norisoprenoids, non-conjugated steroids, in particular androstane and pregnane steroids, and comparable non-conjugated compounds.

L'invention concerne un procédé d'obtention d'un extrait contenant le mélange naturel d'oestrogènes équins conjugués. Ce procédé se caractérise en ce que le mélange d'oestrogènes conjugués obtenu par extraction en phase solide à partir de l'urine de juments gravides est appauvri en constituants phénoliques de l'urée et en composés lipophiles non conjugués choisis dans le groupe comprenant des flavonoïdes non conjugués, des isoflavonoïdes non conjugués, des norisoprénoïdes non conjugués, des stéroïdes non conjugués, en particulier des stéroïdes androstanes et pregnanes, et des composés non conjugués analogues.

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