Method for obtaining an increased production of a producing...

Details Method for obtaining an increased production of a producing... Method for obtaining an increased production of a producing...

C - Chemistry, Metallurgy

12

N

C12N 15/02 (2006.01) C07K 14/755 (2006.01) C12N 5/12 (2006.01) C12N 5/16 (2006.01) C12N 13/00 (2006.01) C12N 15/11 (2006.01)

Patent

CA 2156181

The invention relates to a method for obtaining a higher product expression in a producing mammalian celline characterized by treating the original celline with itself according to a fusion protocol known in the art. The production of protein products is performed in mammalian tissue culture, and the product could be therapeutic proteins or other molecules intended for human use. In particular this invention relates to the use of cell fusion methods to obtain a stable high producing celline.

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