Method for obtaining cells with new properties

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 1/20 (2006.01) C12N 15/01 (2006.01) C12N 15/09 (2006.01) C12N 15/70 (2006.01)

Patent

CA 2453176

The present invention relates to a method for generating a novel form of life comprising the steps consisting of: a) irreversible alteration of the genome of a microbial clone; b) cultivation of a vast population of microbial cells originating from the altered clone obtained in step a) during numerous generations under conditions allowing selection for a higher and stable proliferation rate; c) isolation of descendant clones within the cultivated population of step b) still bearing the alteration of step a).

L'invention concerne un procédé de génération d'une nouvelle forme de vie, qui consiste à : a) modifier irréversiblement le génome d'un clone microbien ; b) mettre en culture une population nombreuse de cellules microbiennes provenant du clone modifié obtenu dans la phase a) sur de nombreuses générations, dans des conditions permettant la sélection d'une vitesse de prolifération stable et plus élevée ; c) isoler les clones descendants au sein de la population en culture de la phase b) portant encore la modification de la phase a).

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