Method for obtaining of glucose-isomerase

C - Chemistry – Metallurgy – 12 – N

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C12N 9/92 (2006.01)

Patent

CA 1149301

ABSTRACT OF THE DISCLOSURE: The present invention provides a method for obtaining of glucose isomerase wherein the enzyme-producing strain Strepto- myces sp. 1339 registration N. 144 -State Institute for Drugs Control, is cultivated for 36-72 hours in a culture medium with xylose as an indicator, the temperature being kept from 24 to 36°C, the initial Ph of cultivation is from 6,5 to 9.0: the temperature of isomerization is from 50 to 80°C, ph is from 6.0 to 9.0 in the presence of CoCl2?6H2O and concentration of the substrate from 0.1 to 3M.

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