Method for obtaining of glucose-isomerase

C - Chemistry – Metallurgy – 12 – N

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C12N 9/92 (2006.01) C12P 19/24 (2006.01)

Patent

CA 1171010

ABSTRACT OF THE DISCLOSURE The present invention relates to a method for obtaining of glucose isomerase, wherein the enzyme-producing strain Streptomyces sp.No 765 registration N.143 - State Institute for Drugs Control, is cultivated for 36 - 72 hours in a culture medium with xylose as an inductor, the temperature being kept from 24 to 36°C, the initial pH of cultivation is from 6,5 to 9,0; the temperature of izomerization is from 50 to 90°C, pH is from 6,0 to 9,0 in the presence of MgSO4.7H2O in concentration from:1.10 4 to 1.10-2M and substrate concentration from 0,1 to 3M.

365821

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