Method for obtaining polypeptide constructs comprising two...

C - Chemistry – Metallurgy – 07 – K

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C07K 16/46 (2006.01) C07K 16/32 (2006.01)

Patent

CA 2706425

The present invention relates to methods for obtaining a polypeptide construct directed against one or more antigens and/or epitopes and having one or more desired characteristics, wherein the polypeptide construct comprises at least two single domain antibodies. The methods of the present invention involve producing a diversity of polypeptide constructs that are structural variants and screening the produced diversity of polypeptide constructs for a polypeptide construct having said one or more desired characteristics. The present invention further relates to polypeptide constructs directed against one or more antigens and/or epitopes having one or more desired characteristics, wherein the polypeptide construct comprises at least two single domain antibodies. The methods and polypeptide constructs according to the present invention are useful for the identification of optimal therapeutic compounds.

La présente invention porte sur des procédés pour obtenir un produit de construction de polypeptide dirigé contre un ou plusieurs antigènes et/ou épitopes et ayant une ou plusieurs caractéristiques désirées, le produit de construction de polypeptide comprenant au moins deux anticorps à domaine unique. Les procédés de la présente invention mettent en jeu la production d'une diversité de produits de construction de polypeptide qui sont des variants structuraux et le criblage de la diversité produite de produits de construction de polypeptide pour un produit de construction de polypeptide ayant ladite ou lesdites caractéristiques désirées. La présente invention porte en outre sur des produits de construction de polypeptide dirigés contre un ou plusieurs antigènes et/ou épitopes ayant une ou plusieurs caractéristiques désirées, le produit de construction de polypeptide comprenant au moins deux anticorps à domaine unique. Les procédés et produits de construction de polypeptide selon la présente invention sont utiles pour l'identification de composés thérapeutiques optimaux.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Method for obtaining polypeptide constructs comprising two... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for obtaining polypeptide constructs comprising two..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for obtaining polypeptide constructs comprising two... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1453515

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.