Method for obtaining proteins having improved functional...

Details Method for obtaining proteins having improved functional... Method for obtaining proteins having improved functional...

C - Chemistry, Metallurgy

12

N

C12N 15/56 (2006.01) C07K 14/47 (2006.01) C12N 9/00 (2006.01) C12N 9/26 (2006.01) C12N 9/28 (2006.01) C12N 9/42 (2006.01) C12Q 1/00 (2006.01) C12Q 1/34 (2006.01) C12Q 1/37 (2006.01) C12Q 1/40 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2394740

An improved protein comprising an amino acid sequence which has been modified from a precursor amino acid sequence by the substitution or deletion of an amino acid residue which differs from a corresponding amino acid residue in a less stable but homologous protein, wherein said improved protein has improved properties compared to a protein corresponding to the precursor amino acid sequence.

L'invention concerne une protéine améliorée qui comprend une séquence d'acides aminés modifiée à partir d'une séquence d'acides aminés précurseur par substitution ou délétion d'un reste d'acides aminés différent d'un reste d'acides aminés correspondant d'une protéine moins stable mais homologue. La protéine améliorée possède des propriétés améliorées par rapport à une protéine correspondant à la séquence d'acides aminés précurseur.

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