C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 311/08 (2006.01)
Patent
CA 2573859
The invention relates to a method for obtaining pure tetrahydrocannabinol from reaction mixtures containing tetrahydrocannabinol compounds or from raw products containing tetrahydrocannabinol compounds. According to said method, the tetrahydrocannabinol compounds in the reaction mixture or in the raw product are converted into crystallisable derivatives, preferably using a suitable solvent, said derivatives are then crystallised and isolated, and the pure tetrahydrocannabinol compounds are then obtained from the crystallised derivatives. The invention also relates to the use of compounds produced in this way for the production of a medicament for human therapy, and to the medicaments thus produced.
L'invention concerne un procédé de fabrication de tétrahydrocannabinol pur à partir de mélanges de réaction contenant des composés de tétrahydrocannabinol ou d'un produit brut contenant des composés de tétrahydrocannabinol, consistant à transformer le composé de tétrahydrocannabinol du mélange de réaction ou du produit brut en dérivé cristallisable, de préférence au moyen d'un solvant adapté, à séparer le dérivé cristallisable par cristallisation et à l'isoler, puis à fabriquer ensuite le composé de tétrahydrocannabinol pur à partir du dérivé cristallisé. L'invention concerne également l'utilisation des composés ainsi fabriqués pour la fabrication d'un médicament destiné à l'homme, ainsi que les médicaments ainsi fabriqués.
Arslantas Enver
Weigl Ulrich
Cilag Ltd.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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