C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
C12P 7/62 (2006.01)
Patent
CA 2730220
The present invention relates to a method for producing and preparing polyglycolate (PGA) from genetically engi-neered organisms. More specifically, the invention relates to a method comprising two steps; 1) culturing, in a medium containing glycolic acid or not, the microorganism expressing at least one gene encoding an enzyme(s) that converts glycolate into glycolyl--CoA, and a gene encoding polyhydroxyalkanoate (PHA) synthase which uses glycolyl-CoA as a substrate, 2) recovering the polyglycolate polymer.
La présente invention porte sur un procédé pour la fabrication et la préparation de polyglycolate (PGA) à partir d'organismes modifiés par génie génétique. De façon plus spécifique, l'invention porte sur un procédé comprenant deux étapes : 1) la culture, dans un milieu contenant ou non de l'acide glycolique, du micro-organisme exprimant au moins un gène codant pour une ou plusieurs enzymes qui convertissent le glycolate en glycolyl-CoA, et un gène codant pour la polyhydroxyalcanoate (PHA) synthase qui utilise la glycolyl-CoA en tant que substrat, 2) la récupération du polymère polyglycolate.
Dischert Wanda
Soucaille Philippe
Metabolic Explorer
Smart & Biggar
LandOfFree
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