C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C12P 19/34 (2006.01)
Patent
CA 2485968
The presently claimed subject matter provides a method for detecting an autoimmune disorder in a subject by obtaining a biological sample from the subject; determining expression levels of at least two genes in the biological sample; and comparing the expression level of each gene with a standard, wherein the comparing detects the presence of an autoimmune disorder in the subject. Also provided are compositions and kits for carrying out the methods of the presently claimed subject matter.
La présente invention concerne une technique de détection de troubles auto-immuns chez un sujet qui consiste à obtenir un prélèvement biologique de ce sujet, à déterminer les niveaux d'expression d'au moins deux gènes présents dans ce prélèvement biologique et, à comparer le niveau d'expression de chaque gène avec une norme, cette comparaison permettant de détecter la présence d'un trouble auto-immun chez ce sujet. Cette invention concerne aussi des compositions et des kits destinés à mettre en oeuvre les techniques de l'invention.
Aune Thomas M.
Olsen Nancy J.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Vanderbilt University
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