Method for prediction of premature labor

G - Physics – 01 – N

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G01N 33/74 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2143292

A method for detecting the imminent onset of labor in a patient, which comprises analyzing a body fluid of the patient for estriol concentration; correlating the concentration with a standard value; and relating a higher concentration of estriol relative to the standard value as an indication of potential onset of premature labor. The standard is usually selected from the group consist- ing of (I) a predetermined range of estriol concentrations for the body fluid in normal pregnant humans at a preselected time rel- ative to normal, full-term delivery, or (2) a previously measured estriol concentration of the same body fluid of the same pregnant human. Use of this method does not require determination of an estriol/progesterone concentration ratio in the body fluid being test.

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