C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/12 (2006.01) C07D 239/26 (2006.01) C07D 403/06 (2006.01)
Patent
CA 2624020
The present invention concerns the method for preparing (3-chloro-4- fluorophenyl)-(4-fluoro-4-{[(5-methyl-pyrimidin-2- ylmethyl)-amino]-methyl}- piperidin-1-yl)-methanone of formula (II) by condensation between 5-methyl- pyrimidin-2-methylamine of formula (I) and cyanohydrin of formula (III).
La présente invention concerne le procédé de préparation de la (3-chloro-4-fluorophényl)-(4-fluoro-4-{[(5-méthyl-pyrimidin-2-ylméthyl)-amino]-méthyl}-pipéridin-1-yl)-méthanone répondant à la formule (II) par la condensation entre la 5-méthyl-pyrimidin-2-méthylamine répondant à la formule (I) et la cyanohydrine répondant à la formule (III).
Brunel Serge
Maurel Jean-Louis
Vacher Bernard
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Pierre Fabre Medicament
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