Method for preparing a compound for interaction of active...

A - Human Necessities – 61 – K

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

A61K 9/16 (2006.01) A61K 47/48 (2006.01)

Patent

CA 2462537

The invention concerns a method for preparing compounds for interaction of an active substance hardly soluble in an aqueous medium with a porous support. The invention is characterized in that it comprises the following steps: (a) mixing the active substance generated by supercritical fluid and the specific amount of porous support; (b) carrying out a molecular diffusion step by contacting in static mode a supercritical fluid with the mixture obtained at step (a) for the time required to improve the dissolution in the aqueous medium of the mixture obtained at step (a); (c) washing the interactive compound obtained at step (b) with a supercritical fluid flow; (d) recuperating the particles of the interactive compound thus formed. The invention also concerns a compound obtainable by said method.

La présente invention a pour objet un procédé de préparation de composés d'interaction d'une substance active peu soluble dans un milieu aqueux avec un support poreux, caractérisé en ce qu'il comprend les étapes suivantes: (a) mélanger la substance active générée par fluide supercritique et la quantité déterminée de support poreux; (b) mettre en oeuvre une étape de diffusion moléculaire par mise en contact en mode statique d'un fluide supercritique avec le mélange obtenu à l'étape (a) pendant le temps nécessaire pour améliorer la dissolution dans un milieu aqueux du mélange obtenu à l'étape (a); (c) laver le composé d'interaction obtenue à l'étape (b) par un flux de fluide supercritique; (d) récupérer les particules du composé d'interaction ainsi formé. Elle concerne également un composé susceptible d'être obtenu par ce procédé.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Method for preparing a compound for interaction of active... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for preparing a compound for interaction of active..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for preparing a compound for interaction of active... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-2035005

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.