C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 307/33 (2006.01) A61K 31/34 (2006.01) A61K 38/07 (2006.01) C07K 5/10 (2006.01) C07K 5/117 (2006.01)
Patent
CA 2296742
The invention concerns a novel method for preparing compounds of formula (IV) or (I) from racemic alkoxyfuranone of formula (II) in which R1 and R2 are as defined in the description, the said novel compounds of formula (IV) and the intermediate compounds of said method, and the use of compounds of formula (IV) or (I) in the synthesis process of compounds inhibitors of interleukin-1beta converting enzyme.
L'invention a pour objet un nouveau procédé de préparation de composés de formule (IV) ou (I) à partir d'alkyloxyfuranone racémique de formule (II), R1 et R2 étants tels que définis dans la description, les composés nouveaux de formule (IV) ainsi que les composés intermédiaires de ce procédé, et l'utilisation des composés de formule (IV) ou (I) dans le procédé de synthèse de composés inhibiteurs de l'enzyme de conversion de l'interleukine-1bêta.
Bouchet Raphael
Brion Francis
Colladant Colette
Lagouardat Jacques
Aventis Pharma S.a.
Hoechst Marion Roussel
Robic
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