Method for preparing closed vesicles

Details Method for preparing closed vesicles Method for preparing closed vesicles

A - Human Necessities

61

K

A61K 9/127 (2006.01)

Patent

CA 2202103

A method for preparing a closed vesicle by a rehydration of a closed vesicle using a rehydration solution, wherein said closed vesicle comprises a dehydrated micelle particle or dehydrated amphipathic micelle bilayers, preferably a liposome loading a pharmaceutically active substance, and the method is characterized in that the rehydration is carried out at a low temperature such as in the range of from 0°C to 10°C. The method can provides a rehydrated stable vesicle without a leak of the loaded substance.

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