Method for preparing coating compositions containing an...

G - Physics – 01 – N

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167/139, 167/44

G01N 33/545 (2006.01) G01N 33/549 (2006.01) G01N 33/573 (2006.01)

Patent

CA 1251394

-0- METHOD FOR PREPARING COATING COMPOSITIONS CONTAINING AN IMMUNOLOGICALLY REACTIVE SPECIES AND ELEMENTS CONTAINING SAME Abstract of the Disclosure A method for preparing a blush polymer coating composition containing an immunologically reactive species comprises milling the species and the other materials used in the composition to uni- formly disperse the species therein. This coating composition can be used to prepare analytical ele- ments for determining analytes (e.g. creatine kinase-MB) whereby the effects of potential inter- ferents are immunochemically removed. By milling the immunologically reactive species, e.g. antisera, into the coating composition, the resulting element his improved stability resulting in improved keeping in high humidity environments.

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