Method for preparing compositions for transferring nucleic...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/88 (2006.01) A61K 9/127 (2006.01) A61K 31/70 (2006.01) A61K 47/48 (2006.01) A61K 48/00 (2006.01) C12N 15/87 (2006.01)

Patent

CA 2267187

The invention concerns a method for preparing a composition for transferring nucleic acids consisting in contacting a nucleic acid with a cationic lipid, whereby, previous to contacting, the cationic lipid is subjected to a heating step. The invention also concerns the resulting compositions and their use.

La présente invention concerne un procédé de préparation d'une composition pour le transfert d'acides nucléiques comprenant la mise en contact d'un acide nucléique avec un lipide cationique, selon lequel, préalablement à la mise en contact, le lipide cationique est soumis à une étape de chauffage. L'invention concerne également les compositions obtenues et leur utilisation.

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