Method for preparing cyclohexane carboxylic acids

Details Method for preparing cyclohexane carboxylic acids Method for preparing cyclohexane carboxylic acids

C - Chemistry, Metallurgy

07

C

C07C 225/00 (2006.01) A61K 8/73 (2006.01) A61K 8/81 (2006.01) C07C 253/30 (2006.01) C07C 255/37 (2006.01) C07C 255/46 (2006.01)

Patent

CA 2381011

This invention relates to a method for preparing 4-substituted-4- cyanocyclohexane carboxylates by forming the cyclohexane ring by treating a .alpha.,.alpha.-bis(2-haloethyl)-4-benzeneacetonitrile with a dialkyl malonate and decarboxylating the resulting diester.

L'invention concerne un procédé permettant de préparer des 4-cyanocyclohexane carboxylates 4-substitués, par formation d'un noyau de cyclohexane à l'aide d'un traitement d'un .alpha.,.alpha.-bis(2-haloethyl)-4-benzèneacétonitrile avec un malonate de dialkyle et par décarbonxylation du diester obtenu.

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