C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/071 (2010.01) C12M 3/04 (2006.01)
Patent
CA 2532418
A method for preparing a human or animal tissue by applying a compressive force to a stack of sheets of living tissue thereby inducing adjacent layers to fuse or adhere to each other. The force is applied in direction normal to the surface of the tissue. A multi-layer tissue produced by the method decribed above can also possess at least two different types of sheets and/or consist essentially of between two and twelve sheets of living tissue. The method can also be used to prepare a planar tissue that can further be incorporated in a multi-layer tissue construct. The methods and tissues described herein are useful for the preparation of engineered tissues.
L'invention concerne un procédé de préparation d'un tissu humain ou animal, qui consiste à appliquer une force de compression sur un empilement de couches de tissu vivant pour amener des couches adjacentes à fusionner ou coller l'une contre l'autre. La force est appliquée dans le sens naturel de la surface du tissu. Un tissu multicouche produit par le procédé de l'invention peut également présenter au moins deux types de couches différents et/ou se composer essentiellement de deux à douze couches de tissu vivant. Le procédé de l'invention peut également être utilisé pour préparer un tissu planaire pouvant être incorporé dans une structure tissulaire multicouche. Les procédés et tissus de l'invention sont utiles pour la préparation de tissus techniques.
Auger Francois
Bergeron Francois
Germain Lucie
Roberge Charles
Biogentis Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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