C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 233/74 (2006.01) A01N 43/50 (2006.01) B27K 3/00 (2006.01) C07D 233/78 (2006.01) C09D 5/14 (2006.01) C11D 3/48 (2006.01) A61K 7/00 (1990.01)
Patent
CA 2093045
Compositions of dimethyloldimethylhydantoin, monomethyloldimethylhydantoin, and dimethylhydantoin having less than 0.1% by weight of free formaldehyde based upon 100% by weight of total composition; and wherein the weight ratio of di- methyloldimethylhydantoin to monomethyloldimethylhydantoin ranges from about 1:1.25 to about 3.5:1, are provided. These compositions may be prepared (1) by reacting dimethylhydantoin and a formaldehyde-containing source wherein the molar ratio of formal- dehyde to dimethylhydantoin ranges from about 1.2:1 to about 1.55:1 or (2) by admixing (a) from about 80 to about 90% by weight of an aqueous solution of methyloldimethylhydantoin having greater than about 0.1% by weight of free formaldehyde with (b) about 20 to about 10% by weight of dimethylhydantoin based upon 100% weight of aqueous dimethyloldimethylhydantoin solution and dimethylhydantoin combined. The compositions are useful as, inter alia, antimicrobial agents useful to extend the shelf life of various preparations susceptible to microbial growth.
Farina Thomas E.
Rosen Marvin
Lonza Inc.
Mccarthy Tetrault Llp
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