Method for preparing low-substituted cellulose ethers

C - Chemistry – Metallurgy – 08 – B

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C08B 11/00 (2006.01) A61K 9/20 (2006.01) C08B 11/20 (2006.01)

Patent

CA 1042878

ABSTRACT OF THE DISCLOSURE In the process for the preparation of low-substituted cellulose ethers comprising the successive steps of etherification of alkali cellulose, neutralization of the crude cellulose ether, washing, drying and pulverization, the neutralization step is carried out in two stages, i.e., by first employing 5 to 80% of an acid stoichiometrically required and then adding an additional amount of the acid to complete neutralization. The cellulose ethers thus prepared can readily be pulverized into fine powder having a very good flowing property and yet an excellent binding force, and work as a suitable disintegrator in tablets.

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