Method for preparing n-monosubstituted and...

Details Method for preparing n-monosubstituted and... Method for preparing n-monosubstituted and...

C - Chemistry, Metallurgy

07

D

C07D 243/04 (2006.01) C07D 401/00 (2006.01) C07D 403/00 (2006.01) C07D 405/00 (2006.01) C07D 405/06 (2006.01) C07D 409/00 (2006.01) C07D 413/00 (2006.01) C07D 417/00 (2006.01) C07D 453/02 (2006.01) C07D 455/02 (2006.01) C07D 471/04 (2006.01) C07D 473/00 (2006.01) C07D 475/00 (2006.01) C07D 491/04 (2006.01) C07D 495/04 (2006.01) C07D 498/04 (2006.01) C07D 513/04 (2006.01) C07F 7/10 (2006.01) C07K 1/113 (2006.01)

Patent

CA 2223391

The present invention relates generally to methods for the preparation of unsymmetrically substituted cyclic ureas of formulae (VIa) and (VIb), which are useful as HIV protease inhibitors. The methods provided go through an isourea intermediate.

L'invention concerne, en général, des procédés permettant de préparer des urées cycliques substituées de façon asymétrique, des formules (VIa) et (VIb), utiles en tant qu'inhibiteurs de la VIH protéase. Selon les procédés présentés, on obtient, comme produit intermédiaire, de l'isourée.

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