C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 213/00 (2006.01) C07B 41/02 (2006.01) C07B 53/00 (2006.01) C07C 215/30 (2006.01) C07C 215/00 (2006.01)
Patent
CA 2265568
The invention concerns a method for preparing an optically active alcohol of formula (I) in which the carbon atom indicated by the symbol * can have the configuration (R) or (S) and X represents an amino group not substituted or a mono- or di- (C1-C4)alkylamino group optionally salified from corresponding ketones by catalytic hydrogenation in the presence of one rhodium complex.
La présente invention concerne un procédé de préparation d'un alcool optiquement actif de formule (I), dans laquelle l'atome de carbone indiqué par le symbole * peut avoir la configuration (R) ou (S) et X représente un groupe amino non substitué ou un groupe mono- ou di-(C¿1?-C¿4?)alkylamino éventuellement salifié à partir des cétones correspondantes par hydrogénation catalytique en présence d'un complexe de rhodium.
Agbossou Francine
Devocelle Marc
Dormoy Jean-Robert
Mortreux Andre
Sanofi
Sanofi-Synthelabo
Sim & Mcburney
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