C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/10 (2006.01) C07D 401/14 (2006.01) C07D 403/14 (2006.01)
Patent
CA 2461060
A process for preparing a pyrimidinone compound and salts thereof. The method of the present invention enables the convenience to produce the pyrimidinone derivatives in high yields. The pyrimidinone compounds are useful for treating cardiovascular diseases caused by binding of angiotensin II to its receptors, through antagonistic activity against angiotensin II receptors. (see formula 1)
L'invention concerne un procédé de fabrication de composés pyrimidinone et de sels pharmaceutiquement acceptables de ces composés. Le procédé selon l'invention permet de fabriquer avec un rendement élevé des dérivés pyrimidinone servant au traitement de maladies cardiovasculaires provoquées par liaison d'angiotensine II à ses récepteurs, lesdits composés agissant de façon antagoniste contre les récepteurs d'angiotensine II.
Kim Ji-Han
Kim Sang-Lin
Lee Jung-Bok
Tan Hyun-Kwang
Yoo Byoung-Wug
Boryung Pharmaceutical Co. Ltd.
Ridout & Maybee Llp
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