G - Physics – 02 – B
Patent
G - Physics
02
B
G02B 1/04 (2006.01) C08F 290/06 (2006.01)
Patent
CA 2630854
The present invention provides a method and a formulation for consistently producing a silicone hydrogel material having relatively high oxygen permeability, relatively high ion permeability, and low modulus, and contact lenses prepared from a formulation of the invention or made of a silicone hydrogel material of the invention. The method for making silicone-hydrogel contact lenses, comprising steps of: obtaining a polymerizable fluid composition including a siloxane-containing macromer with ethylenically unsaturated group(s), a radical initiator, and an organonitroxide, wherein the organonitrioxide is a compound having the formula (1) of: in which R1, and R2 are independently H, an alky] group, a cycloalkyl group, an arenyl group, a heterocyclic group, or an aryl group; R3 is an alkyl group, a cycloalkyl group, an arenyl group, a heterocyclic group, or an aryl group; R3 and R2 or R1 and R2 may be joined together to form a cyclic ring structure that may have fused with it another saturated or aromatic ring; each of R1, R2, or R3 may be substituted by at least one member of the group consisting of hydroxy) group, sulfonate group, sulfate group, carboxylate group, amino group, ammonium group, alkoxy group, aryloxy group, silyl group, boryl group, phosphino group, thio group, seieno group, and combinations thereof.
La présente invention concerne une méthode et une formule pour la production fiable d'un matériel de type hydrogel de silicone ayant une perméabilité vis-à-vis de l'oxygène relativement élevée, une perméabilité ionique relativement élevée et un module de traction faible, ainsi que des lentilles de contact préparées à partir d'une formule selon l'invention ou fabriquées à partir d'un matériel de type hydrogel de silicone selon l'invention.
Fetherstonhaugh & Co.
Novartis Ag
LandOfFree
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