Method for preparing substrates having immobilized molecules...

G - Physics – 01 – N

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G01N 33/543 (2006.01) C07F 7/18 (2006.01) C08G 18/00 (2006.01) C08L 83/04 (2006.01) C12Q 1/68 (2006.01) G01N 33/552 (2006.01)

Patent

CA 2563510

A method for the efficient immobilization of molecules onto substrate surfaces that employs an isocyanate compound to form a reactive isocyanate surface, nanoparticles onto surfaces as well as silylated molecules such as silylated oligonucleotides or proteins onto unmodified surfaces such as a glass surface is provided. Also provided are compounds, devices, and kits for modifying surfaces such as glass surfaces.

La présente invention a trait à l'immobilisation efficace de molécules sur des surfaces de substrat mettant en oeuvre un composé à base d'isocyanate pour la formation d'une surface d'isocyanate réactive, des nanoparticules sur des surfaces ainsi que des molécules ayant été soumises à une silylation telles que des oligonucléotides ou des protéines ayant été soumis à une silylation sur des surfaces non modifiées telles qu'une surface de verre. L'invention a également trait à des composés, dispositifs, et trousses pour la modification de surfaces telles que des surfaces de verre.

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