Method for preparing suspension of stable posiplexes

C - Chemistry – Metallurgy – 12 – N

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C12N 15/87 (2006.01) A61K 9/127 (2006.01) A61K 47/18 (2006.01) A61K 47/20 (2006.01) A61K 48/00 (2006.01) C12N 15/88 (2006.01)

Patent

CA 2352535

Described are stable posiplexes and homogenous suspension of stable posiplexes that can be used to deliver nucleic acid to a cell for the purpose of providing a therapeutic molecule to the cells of an individual in need of such treatment. Furthermore, methods for the preparation of stable posiplexes and homogenous suspension thereof are provided.

L'invention porte sur des posiplexes stables et sur une suspension homogène de posiplexes stables pouvant être utilisés pour acheminer l'acide nucléique vers une cellule en vue d'administrer une molécule thérapeutique aux cellules d'un individu nécessitant ce traitement. L'invention porte, de plus, sur des procédés de préparation de posiplexes stables et de la suspension homogène qu'ils forment.

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